New Aids Strain
Nineteen
Join Date: 2003-12-23 Member: 24701Members
in Discussions
i got it fom another message board
some messed up ****
I got this from the Drudge Report...pretty crazy...
NYC Health Officials Find New, Virulent HIV Strain (Update7)
Feb. 11 (Bloomberg) -- New York City doctors have discovered a man with a previously unseen strain of HIV that is resistant to three of the four types of anti-viral drugs that combat the disease, and progresses from infection to full-blown AIDS in two or three months, the health department said.
``We've identified this strain of HIV that is difficult or impossible to treat and which appears to progress rapidly to AIDS,'' said New York City Health Commissioner Thomas Frieden. ``We have not seen a case like this before. It holds the potential for a very serious public health problem.''
The case was diagnosed in a New Yorker in his mid-40s who reported multiple male sex partners and unprotected anal sex -- often while using the drug crystal methamphetamine.
``It is likely there are others infected with this strain and this individual has infected others,'' Frieden said. The case is ``extremely concerning and a wake-up call,'' he said.
Antonio Urbina, medical director of HIV education and training at St. Vincent's Catholic Medical Center, site of one of Manhattan's largest AIDS clinics, said the patient's use of crystal methamphetamine shows that the drug ``continues to play a significant role in facilitating the transmission of HIV.'' The drug reduces peoples' inhibitions and their likelihood of using condoms or other forms of safe sex, he said.
`Alarming'
While drug resistance is increasingly common among patients who have been treated for HIV, cases of three-class antiretroviral-resistant HIV -- or 3-DCR HIV -- in newly diagnosed, previously untreated patients are extremely rare, and the combination of this pattern of drug resistance and rapid progression to AIDS may not have been seen previously, the health department said in a news release.
The strain found in New York was ``highly unusual,'' said Ronald Valdiserri, 53, deputy director of the National Center for HIV, Sexually Transmitted Diseases and Tuberculosis at the U.S. Centers for Disease Control and Prevention, in an interview.
``We're talking about a single case, but clearly the fact that we are dealing with such broad resistance of drugs and the rapid clinical progression is quite alarming,'' Valdiserri said.
U.S. health officials intend to contact clinics across the country to set up a surveillance system for the HIV strain, he said. City officials are working to identify, contact and counsel the patient's sex partners, Frieden said.
Fuzeon
Frieden said the one drug the HIV strain isn't resistant to is Enfuvirtide, sold under the trade name Fuzeon, developed by Trimeris Inc. of Durham, North Carolina, and Roche Holding AG of Switzerland. The problem, Frieden and other physicians said, is that this drug is most effective when used in a ``cocktail'' with other retrovirus drugs such as nucleoside reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitors and protease inhibitors.
Trimeris stock closed at $13.60, up 86 cents or 6.75 percent, in composite trading on the Nasdaq, the biggest single- day percentage gain since Sept. 10, when it rose 11.49 percent, and down $4.63 from $17.93 a year ago. Roche shares traded at 123.2 Swiss Francs, up 0.5 francs, in composite trading in Zurich, down six Swiss Francs from a year ago.
The news ``is probably positive for Trimeris,'' said Sharon Seiler, a biotech analyst with New York-based Punk, Ziegel & Co., which she said owns no shares in the company, though it does act as a market maker. Fuzeon's required twice-daily injections and the need to mix the solution for 20 minutes ``have been significant impediments to the drug's sales'' in two years on the market, she said.
Fast Onset
The drug, which costs a patient an average $20,000, is the first in a class called fusion inhibitors that work by preventing HIV from infecting healthy cells.
The infected New Yorker had gone for AIDS tests frequently over the years and tested negatively until December, when he tested positive for the virus, Frieden said. Physicians believe he became infected in October.
``In this patient's case, onset of AIDS appears to have occurred within two or three months and at most 20 months after HIV infection,'' Frieden said. The patient, whose name was withheld, has symptoms usually associated ``with someone who has very advanced disease,'' he said.
The normal time of progression from infection to full-blown AIDS in an untreated patient is about nine years, with death following within 18 months, said Karlie Stanton, a spokeswoman for the CDC in Atlanta. For someone treated with anti-viral drugs, the average progression to disease from infection is 11 years, with death occurring within an average six years, Stanton said.
Watching for Cases
Doctors at the Aaron Diamond AIDS Research Center in Manhattan diagnosed the patient, Frieden said. David Ho, director of the center, said that while this represents a single case, ``it is prudent to closely watch for any additional possible cases while continuing to emphasize the importance of reducing HIV risk behavior.''
Persons diagnosed and living with HIV/AIDS in New York City totaled 88,479 out of a total population of 7.3 million in calendar year 2003, the last year in which statistics are available.
some messed up ****
I got this from the Drudge Report...pretty crazy...
NYC Health Officials Find New, Virulent HIV Strain (Update7)
Feb. 11 (Bloomberg) -- New York City doctors have discovered a man with a previously unseen strain of HIV that is resistant to three of the four types of anti-viral drugs that combat the disease, and progresses from infection to full-blown AIDS in two or three months, the health department said.
``We've identified this strain of HIV that is difficult or impossible to treat and which appears to progress rapidly to AIDS,'' said New York City Health Commissioner Thomas Frieden. ``We have not seen a case like this before. It holds the potential for a very serious public health problem.''
The case was diagnosed in a New Yorker in his mid-40s who reported multiple male sex partners and unprotected anal sex -- often while using the drug crystal methamphetamine.
``It is likely there are others infected with this strain and this individual has infected others,'' Frieden said. The case is ``extremely concerning and a wake-up call,'' he said.
Antonio Urbina, medical director of HIV education and training at St. Vincent's Catholic Medical Center, site of one of Manhattan's largest AIDS clinics, said the patient's use of crystal methamphetamine shows that the drug ``continues to play a significant role in facilitating the transmission of HIV.'' The drug reduces peoples' inhibitions and their likelihood of using condoms or other forms of safe sex, he said.
`Alarming'
While drug resistance is increasingly common among patients who have been treated for HIV, cases of three-class antiretroviral-resistant HIV -- or 3-DCR HIV -- in newly diagnosed, previously untreated patients are extremely rare, and the combination of this pattern of drug resistance and rapid progression to AIDS may not have been seen previously, the health department said in a news release.
The strain found in New York was ``highly unusual,'' said Ronald Valdiserri, 53, deputy director of the National Center for HIV, Sexually Transmitted Diseases and Tuberculosis at the U.S. Centers for Disease Control and Prevention, in an interview.
``We're talking about a single case, but clearly the fact that we are dealing with such broad resistance of drugs and the rapid clinical progression is quite alarming,'' Valdiserri said.
U.S. health officials intend to contact clinics across the country to set up a surveillance system for the HIV strain, he said. City officials are working to identify, contact and counsel the patient's sex partners, Frieden said.
Fuzeon
Frieden said the one drug the HIV strain isn't resistant to is Enfuvirtide, sold under the trade name Fuzeon, developed by Trimeris Inc. of Durham, North Carolina, and Roche Holding AG of Switzerland. The problem, Frieden and other physicians said, is that this drug is most effective when used in a ``cocktail'' with other retrovirus drugs such as nucleoside reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitors and protease inhibitors.
Trimeris stock closed at $13.60, up 86 cents or 6.75 percent, in composite trading on the Nasdaq, the biggest single- day percentage gain since Sept. 10, when it rose 11.49 percent, and down $4.63 from $17.93 a year ago. Roche shares traded at 123.2 Swiss Francs, up 0.5 francs, in composite trading in Zurich, down six Swiss Francs from a year ago.
The news ``is probably positive for Trimeris,'' said Sharon Seiler, a biotech analyst with New York-based Punk, Ziegel & Co., which she said owns no shares in the company, though it does act as a market maker. Fuzeon's required twice-daily injections and the need to mix the solution for 20 minutes ``have been significant impediments to the drug's sales'' in two years on the market, she said.
Fast Onset
The drug, which costs a patient an average $20,000, is the first in a class called fusion inhibitors that work by preventing HIV from infecting healthy cells.
The infected New Yorker had gone for AIDS tests frequently over the years and tested negatively until December, when he tested positive for the virus, Frieden said. Physicians believe he became infected in October.
``In this patient's case, onset of AIDS appears to have occurred within two or three months and at most 20 months after HIV infection,'' Frieden said. The patient, whose name was withheld, has symptoms usually associated ``with someone who has very advanced disease,'' he said.
The normal time of progression from infection to full-blown AIDS in an untreated patient is about nine years, with death following within 18 months, said Karlie Stanton, a spokeswoman for the CDC in Atlanta. For someone treated with anti-viral drugs, the average progression to disease from infection is 11 years, with death occurring within an average six years, Stanton said.
Watching for Cases
Doctors at the Aaron Diamond AIDS Research Center in Manhattan diagnosed the patient, Frieden said. David Ho, director of the center, said that while this represents a single case, ``it is prudent to closely watch for any additional possible cases while continuing to emphasize the importance of reducing HIV risk behavior.''
Persons diagnosed and living with HIV/AIDS in New York City totaled 88,479 out of a total population of 7.3 million in calendar year 2003, the last year in which statistics are available.
Comments
If the new strain causes AIDS to break out faster, that means it's actually less dangerous, because infected people will have less time to infect others.
If the new strain causes AIDS to break out faster, that means it's actually less dangerous, because infected people will have less time to infect others. <!--QuoteEnd--> </td></tr></table><div class='postcolor'> <!--QuoteEEnd-->
I actually thought that when I first read, however "fast" in this case is still a few months, plenty of time to infect at least a few other people. It's a bit better than the years of dormancy other strains exhibit, but I think the drug resistance more than makes up for that. <!--emo&::marine::--><img src='http://www.unknownworlds.com/forums/html/emoticons/marine.gif' border='0' style='vertical-align:middle' alt='marine.gif' /><!--endemo-->
This has actually been known for some time, in fact, there are HIV strains that are known from African patients that are resistant to <i>everything</i> that can be thrown at them. Put simply, when you have a static unchanging drug against one of the most rapidly known mutating viruses around, you are <i>going</i> to lose the war against it eventually. All we can do is come up with new drugs that get around the resistance.
Sadly, this is merely a predictable result to me rather than a surprise <!--emo&:(--><img src='http://www.unknownworlds.com/forums/html/emoticons/sad-fix.gif' border='0' style='vertical-align:middle' alt='sad-fix.gif' /><!--endemo-->
Pretty much, but the main way to get it through drugs is injecting such as heroin, cocaine (the liquid stuff) and a few other injectables. Sharing needles is probably one of the more common ways of getting it. Unprotected sex with lots of people is a good way of getting it too, particularly if you are mingling with IVD users as well.
Overall though, you're more likely to get Chlamydia, Gonnorhea or other STDs well before you would get aids.
Quoted for troof.
Yay, I'm gonna live! *gets hit by train*
I don't know if this view is maybe too radical, but... if someone gets the virus by unprotected sex/sharing of needles, maybe they deserve to die? (that was hard to say, me being a nice person). If they know that they will get AIDS from doing the aforementioned activities, and they still do it... who's at fault here, and why should we be helping?
It's 2 am and I'm falling asleep, sorry if anything sounded too harsh.
I don't know if this view is maybe too radical, but... if someone gets the virus by unprotected sex/sharing of needles, maybe they deserve to die? (that was hard to say, me being a nice person). If they know that they will get AIDS from doing the aforementioned activities, and they still do it... who's at fault here, and why should we be helping?
It's 2 am and I'm falling asleep, sorry if anything sounded too harsh. <!--QuoteEnd--> </td></tr></table><div class='postcolor'> <!--QuoteEEnd-->
Junkies who share needles sometimes have a good idea what they are doing to themselves, but does someone deserve to die because they got drunk at a party and had unprotected sex with somebody?
The only people i can say are at fault here are the people who DO know they are infected and spread the disease.
Pretty much, but the main way to get it through drugs is injecting such as heroin, cocaine (the liquid stuff) and a few other injectables. Sharing needles is probably one of the more common ways of getting it. Unprotected sex with lots of people is a good way of getting it too, particularly if you are mingling with IVD users as well.
Overall though, you're more likely to get Chlamydia, Gonnorhea or other STDs well before you would get aids. <!--QuoteEnd--> </td></tr></table><div class='postcolor'> <!--QuoteEEnd-->
Right, but meth affects your judgement in some pretty adverse ways, and can be a huge contirbuting factor in some behavioral choices.
I read an article a while ago that had a quote from a guy somewhere in africa that went something like this. "If we have sex we get aids and die, but if we don't have sex we'll all die out anyways."
I don't know if this view is maybe too radical, but... if someone gets the virus by unprotected sex/sharing of needles, maybe they deserve to die? (that was hard to say, me being a nice person). If they know that they will get AIDS from doing the aforementioned activities, and they still do it... who's at fault here, and why should we be helping?
It's 2 am and I'm falling asleep, sorry if anything sounded too harsh. <!--QuoteEnd--></td></tr></table><div class='postcolor'><!--QuoteEEnd-->
Junkies who share needles sometimes have a good idea what they are doing to themselves, but does someone deserve to die because they got drunk at a party and had unprotected sex with somebody?
The only people i can say are at fault here are the people who DO know they are infected and spread the disease. <!--QuoteEnd--></td></tr></table><div class='postcolor'><!--QuoteEEnd-->
People with the disease need to wear a sticker on their underwear as an ID badge. Voila, no more transmission.
you can thank monkeys in africa and 60's orgies for that one
you can thank monkeys in africa and 60's orgies for that one <!--QuoteEnd--> </td></tr></table><div class='postcolor'> <!--QuoteEEnd-->
I'll thank a clandestine government lab with horrible intentions.
you can thank monkeys in africa and 60's orgies for that one <!--QuoteEnd--></td></tr></table><div class='postcolor'><!--QuoteEEnd-->
I'll thank a clandestine government lab with horrible intentions. <!--QuoteEnd--> </td></tr></table><div class='postcolor'> <!--QuoteEEnd-->
No. There is absolutely no evidence that AIDs is an engineered virus, and the first recorded incident of the disease was in 1953, science had only recently discovered that DNA was the genetic material that organisms used. They didn't even know how to manipulate it or how to use bacterial/viral systems to do so.
This idea is completely bunk.
you can thank monkeys in africa and 60's orgies for that one <!--QuoteEnd--></td></tr></table><div class='postcolor'><!--QuoteEEnd-->
I'll thank a clandestine government lab with horrible intentions. <!--QuoteEnd--></td></tr></table><div class='postcolor'><!--QuoteEEnd-->
No. There is absolutely no evidence that AIDs is an engineered virus, and the first recorded incident of the disease was in 1953, science had only recently discovered that DNA was the genetic material that organisms used. They didn't even know how to manipulate it or how to use bacterial/viral systems to do so.
This idea is completely bunk. <!--QuoteEnd--> </td></tr></table><div class='postcolor'> <!--QuoteEEnd-->
thats just what the goverment WANTS you to think
you can thank monkeys in africa and 60's orgies for that one <!--QuoteEnd--></td></tr></table><div class='postcolor'><!--QuoteEEnd-->
I'll thank a clandestine government lab with horrible intentions. <!--QuoteEnd--></td></tr></table><div class='postcolor'><!--QuoteEEnd-->
No. There is absolutely no evidence that AIDs is an engineered virus, and the first recorded incident of the disease was in 1953, science had only recently discovered that DNA was the genetic material that organisms used. They didn't even know how to manipulate it or how to use bacterial/viral systems to do so.
This idea is completely bunk. <!--QuoteEnd--></td></tr></table><div class='postcolor'><!--QuoteEEnd-->
thats just what the goverment WANTS you to think <!--QuoteEnd--> </td></tr></table><div class='postcolor'> <!--QuoteEEnd-->
hahaha couldn't have said it better
you can thank monkeys in africa and 60's orgies for that one <!--QuoteEnd--></td></tr></table><div class='postcolor'><!--QuoteEEnd-->
I'll thank a clandestine government lab with horrible intentions. <!--QuoteEnd--></td></tr></table><div class='postcolor'><!--QuoteEEnd-->
No. There is absolutely no evidence that AIDs is an engineered virus, and the first recorded incident of the disease was in 1953, science had only recently discovered that DNA was the genetic material that organisms used. They didn't even know how to manipulate it or how to use bacterial/viral systems to do so.
This idea is completely bunk. <!--QuoteEnd--> </td></tr></table><div class='postcolor'> <!--QuoteEEnd-->
So says the reports made out convieniently by a federal office.
you can thank monkeys in africa and 60's orgies for that one <!--QuoteEnd--></td></tr></table><div class='postcolor'><!--QuoteEEnd-->
I'll thank a clandestine government lab with horrible intentions. <!--QuoteEnd--></td></tr></table><div class='postcolor'><!--QuoteEEnd-->
No. There is absolutely no evidence that AIDs is an engineered virus, and the first recorded incident of the disease was in 1953, science had only recently discovered that DNA was the genetic material that organisms used. They didn't even know how to manipulate it or how to use bacterial/viral systems to do so.
This idea is completely bunk. <!--QuoteEnd--></td></tr></table><div class='postcolor'><!--QuoteEEnd-->
So says the reports made out convieniently by a federal office. <!--QuoteEnd--></td></tr></table><div class='postcolor'><!--QuoteEEnd-->
No, and it is worth noting that samples are still available from the individual who died of the infection in 1953, and that he was infected by HIV has been ratified by several independant laboratories around the world.
HIV is very definitely a natural virus, of which there are several definite animal reservoirs in different primates (Chimps just have the closest related strain). There are also forms of HIV that exist in dogs and cats as well, it's a pretty old virus that has just found a new host. No conspiracy crap involved whatsoever.
Nineteen.
<!--QuoteBegin--></div><table border='0' align='center' width='95%' cellpadding='3' cellspacing='1'><tr><td><b>QUOTE</b> </td></tr><tr><td id='QUOTE'><!--QuoteEBegin--> hahaha couldn't have said it with more <i>general ignorance</i><!--QuoteEnd--></td></tr></table><div class='postcolor'><!--QuoteEEnd-->
I fixed your statement for you.
There isn't a single scrap of evidence to suggest HIV is engineered. Of course, if you have any actual scientific evidence that HIV is engineered, I wouldn't mind reading it, but bear in mind that links various poorly designed websites will not be considered as 'evidence'. You can try searching <a href='http://www.ncbi.nlm.nih.gov/entrez/query.fcgi' target='_blank'>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi</a> for a good start. Then of course we can go into the other group of whack jobs who claim HIV <i>isn't</i> the cause of AIDs and have even more fun because they accept HIV is a natural virus, but it's not the one that causes AIDs.
Nineteen.
<!--QuoteBegin--></div><table border='0' align='center' width='95%' cellpadding='3' cellspacing='1'><tr><td><b>QUOTE</b> </td></tr><tr><td id='QUOTE'><!--QuoteEBegin--> hahaha couldn't have said it with more <i>general ignorance</i><!--QuoteEnd--></td></tr></table><div class='postcolor'><!--QuoteEEnd-->
I fixed your statement for you.
<!--QuoteEnd--> </td></tr></table><div class='postcolor'> <!--QuoteEEnd-->
your damn right **** humor, do you honestly think anyone with the capacity to reach this website could have said that seriously to an obviously joking statement like "thats what they want you to think". so do you have to come back saying im ignorant for making a joke?
and yes it probably is natural but the fact of the matter is that any intelligent person questions what they see around them.
I've had an entire 12 page argument with someone trying to prove that aspartame of all things is a deliberate ploy by the sugar industry to give people brain cancer and diabetes. Quite frankly, nothing surprises me anymore with what kind of crap people will come out with on the internet, absolutely nothing. See some of the previous science related threads on this forum for some prime examples.
<!--QuoteBegin--></div><table border='0' align='center' width='95%' cellpadding='3' cellspacing='1'><tr><td><b>QUOTE</b> </td></tr><tr><td id='QUOTE'><!--QuoteEBegin-->and yes it <i>definitely</i> is natural but the fact of the matter is that any intelligent person questions what they see around them.<!--QuoteEnd--></td></tr></table><div class='postcolor'><!--QuoteEEnd-->
There isn't 'probable' as a part of it. If someone engineered a virus it would stick out like a sore thumb and be so hideously obvious even an undergraduate student could pick it up.
Incidently, I've had this debate before and several times now so you're 'joking' statement is actually meant seriously in a LOT of cases by people (again, isn't the internet wonderful?). Believe it or not, there are more than enough people sufficiently stupid to believe that HIV is engineered and in fact, it usually goes hand in hand with anti-genetic engineering arguments. Mae Won Ho for example claims that HIV is a virus that was 'produced' by the by-products of procedures used to make GE crops.
No statement is too ridiculous for me not to believe it is intended as being serious anymore sadly.
(PS: I'm also a big old meanie).
you can thank monkeys in africa and 60's orgies for that one <!--QuoteEnd--> </td></tr></table><div class='postcolor'> <!--QuoteEEnd-->
Yeah. Damn those 60's orgies.
and I think i must "study" these orgies further....
Maybe they don't deserve to die, but they do know what getting drunk will do to them and if they don't take adaquate precautions they don't really have a right to comlpain when the **** hits the fan.
<!--QuoteEnd--></td></tr></table><div class='postcolor'><!--QuoteEEnd-->
Anyone else notice this? Wonder how he told that to the news press =/
Wouldn't the world be a better place if we all just masturbated? Decrease overpopulation, decrease STDS, but still have fun =D