Something that the current NS lacks and what the new one needs is some sort of training room. For newcomers, Natural Selection is a confusing game, especially if you want to learn how to comm.
What I suggest is to have a Training button on the main screen, once clicked, you will be given these options:
1. Commander - Once clicked, starts you off in the command chair and there is a run through of each default button and what it does. Then you could run little scenarios so you can get practice (Example - marine needs ammo in one spot and another needs health, this way you get practice quick switching and using the keys). There could even be a voice to guide you through the steps of it all instead of having words flash across the screen.
2. Marine - Starts you off as a marine. Shows you how to build, where to go for res nodes and what not. There could even be some target fields with cardboard cutouts of alien lifeforms.
3. Skulk - Goes through the basics of being a skulk, what it can do and its abilities.
I'm hoping you get the picture by now so I am not going to go further in to it with the other lifeforms.
If something like this is made for the game, then you could even turn it in to a pre-release demo. Nothing online, just so NEW players can get the hang of blinking around as a fade or shooting as a marine and of course comming. And yes, I know, people can always play the first one to learn how to do all of this but in order to do that, they need half-life, if they don't have half-life then its $10 which may seem like not that much but it would turn a $30 NS2 purchase (I don't know how much the game will actually cost) in to a $40 one just to learn the game.
This is not friendly to new people. Doing the pre-release demo of just training will get people interested simply because NS %100 original and awesome. If I never touched a pc game before in my life and just downloaded the demo and played as a fade or walked on the walls as a skulk I would think its ****ing cool.
So thats pretty much it, want some feedback.