In one piece, too! ;)
We all know that the kharaa are at their strongest close up. Therein lies the problem - how do you close the distance without getting filled full of holes? Half of combat is removing the gap between you and your prey, so becoming good at it will greatly increase your chances of getting kills.
The basic method of closing the distance is the "run straight at them and die". Most people seem to prefer this tactic, probably because of its ease of execution - you simply run directly at your target in a straight line. This tactic is suprisingly ineffective, unless you are in fact trying to get yourself killed and not your foe.
Ok, seriously, now.
One method is simply zig-zagging across the floor, to your target, but I find that this doesn't work so well because no matter what you do you will
cross your target's stream of fire every time you cross from one side to the other. Yes, it's more effective than the run-straight-and-die, but it's not ideal.
To really close effectively, the idea is to stop their stream from touching you as much as possible. To that end, don't change direction and cross into it. Simple as it sounds, you do that by approaching at an angle to your target. Let's say that there's a line between you and your target (in combat, this line will be a stream of gunfire). The angle between your path and the line is what you're interested in - the greater the angle the safer you are (it's VERY hard to hit someone who's running directly 90 degrees to your gunfire) and the smaller the angle the faster you'll close the distance. Basically, start fairly shallow (about 30 degrees) and increase the angle if you start taking fire (you'll have to react fast, though).
So one way of closing is to simply run right at them, at an angle.
Theoretically, the problem arises when you run out of room. If you're a skulk, however, this isn't a problem because you can run right up the wall.
Closing the distance is essentially about being aware of where the enemy's line of fire is, and staying out of it. It's really that simple. Think of it as a burning laser beam (or something) which you have to avoid at all costs.
Having said that, there are two things which closing the distance is NOT about:
1: an attempt to close as fast
as possible. You aren't going for the fastest kill, you're going for a kill with the most health left over afterwards, so you can make another kill as soon as possible.
2: randomly dodging like crazy. React to the enemy, be aware of where the shots are gong and lead them. It's like playing tennis - you don't just hit the ball wherever you can, you try to lead your opponent in one direction and then hit the ball where they aren't expecting it.
Of course, if you have Leap or similar (you're a Lerk) then you have a speed advantage, but the basic premise is the same.